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Updated: Feb 3, 2026
10:22
Echocardiographic and Histological Examination of Cardiac Morphology in the Mouse
Published on: October 26, 2017
22.7K
When appearances deceive: Echocardiographic changes due to common chest pathology.
Henrik Lynge Hovgaard1,2, Roni Ranghøj Nielsen3,4, Christian B Laursen5
1Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Echocardiography (Mount Kisco, N.Y.)
|October 20, 2018
Summary
Extra-cardiac conditions, like pulmonary embolism and respiratory failure, can alter echocardiography results. Understanding these non-cardiac influences is crucial for accurate cardiac diagnostics and point-of-care ultrasonography.
Area of Science:
- Cardiology
- Pulmonology
- Medical Imaging
Background:
- Echocardiography typically assesses intrinsic cardiac properties.
- Extra-cardiac conditions can significantly alter echocardiographic findings through physiological changes.
Purpose of the Study:
- To highlight how non-cardiac pathologies influence echocardiographic appearance.
- To emphasize the importance of recognizing these indirect cardiac changes.
Main Methods:
- Review of echocardiographic manifestations in extra-cardiac conditions.
- Analysis of physiological alterations caused by pulmonary and mediastinal pathologies.
Main Results:
- Pulmonary embolism and acute respiratory failure can mimic intrinsic cardiac pathology on echocardiography.
- Positive pressure ventilation impacts ventricular hemodynamics, altering echocardiographic assessment.
- Mediastinal pathologies may directly compress the heart, simulating tamponade.
Conclusions:
- Extra-cardiac conditions significantly affect echocardiographic appearance, potentially leading to misinterpretation.
- Knowledge of these influences is vital for accurate echocardiography across all clinical settings.
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