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Perceived Stress and the Fatigue Symptom Cluster in Childhood Brain Tumor Survivors

Ann Johnson1, Marti Rice2, Anne Turner-Henson2

  • 1Texas Christian University.

Oncology Nursing Forum
|October 20, 2018
PubMed

Insights

Brain tumor survivors aged 8-12 years experienced mild to moderate stress, sleep-wake disturbance (SWD), and fatigue. These symptoms and their relationships require regular nursing assessment during survivorship.

Area of Science:

  • Pediatric Oncology
  • Neuro-oncology
  • Child Psychology

Background:

  • Brain tumors significantly impact childhood survivorship.
  • Understanding symptom clusters is crucial for improving quality of life in pediatric cancer survivors.
  • Early survivorship presents unique challenges for children treated for brain tumors.

Purpose of the Study:

  • To investigate the relationships among stress, sleep-wake disturbance (SWD), and fatigue in young brain tumor survivors.
  • To estimate the prevalence and severity of these symptoms in children aged 8-12 years.
  • To identify potential correlations within this symptom cluster.

Main Methods:

  • Cross-sectional study design.
  • Inclusion of child participants treated at Children's Hospital of Alabama and Cook Children's Medical Center.
  • Measurement of child-perceived stress, parent-reported SWD, and fatigue.
  • Biomarker analysis using salivary cortisol levels.
  • Objective sleep assessment via actigraphy.

Main Results:

  • Children reported mild to moderate levels of stress, SWD, and fatigue.
  • A broad spectrum of sleep durations and cortisol levels were observed.
  • Statistically significant relationships were identified between the measured variables, indicating meaningful effect sizes.

Conclusions:

  • The symptom cluster of stress, SWD, and fatigue is prevalent in pediatric brain tumor survivors.
  • These interconnected symptoms warrant routine nursing assessment in early survivorship.
  • Further research may elucidate targeted interventions for managing this symptom cluster.
Abstract

Keywords:
brain tumorcancerchildhoodfatiguesleepstresssurvivorshipsymptom cluster

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