Secondary cardiac risk stratifying tests after coronary computed tomography angiography in emergency department

Vincent A Verheij1, Jan-Erik Scholtz2, Nandini M Meyersohn2

  • 1Department of Emergency Medicine, Massachusetts General Hospital & Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.

Insights

Secondary cardiac risk stratifying tests after coronary computed tomography angiography (CTA) in the emergency department are low, particularly for negative CTA results. Structured post-CTA guidelines are essential for appropriate patient management.

Area of Science:

  • Cardiology
  • Radiology
  • Emergency Medicine

Background:

  • Coronary computed tomography angiography (CTA) in triage strategies has shown increased secondary cardiac risk stratifying tests (SCRSTs).
  • The impact of CTA on SCRSTs in routine emergency department (ED) clinical care is not well-established.
  • This study investigates SCRST rates following the implementation of coronary CTA in an ED setting.

Purpose of the Study:

  • To evaluate the rates of secondary cardiac risk stratifying tests (SCRSTs) after coronary CTA in routine clinical practice.
  • To determine if SCRST rates vary based on coronary CTA results (positive, intermediate, negative, non-diagnostic).
  • To assess adherence to local management recommendations for post-CTA diagnostic strategies.

Main Methods:

  • A single-site retrospective cohort study of ED patients who received coronary CTA between October 1, 2012, and September 30, 2016.
  • SCRSTs included functional cardiac tests and invasive coronary angiography (ICA).
  • Data analysis focused on CTA results and the performance of subsequent SCRSTs.

Main Results:

  • Out of 1916 patients, 9.3% had positive, 5.5% intermediate, 84.1% negative, and 1.1% non-diagnostic CTAs.
  • Overall SCRST rate was 12.4% (5.6% noninvasive, 6.7% ICA).
  • SCRST rates were high after positive (73.7%) and intermediate (72.4%) CTAs, but low after negative (1.1%) and non-diagnostic (47.6%) CTAs.

Conclusions:

  • Routine emergency department coronary CTA is associated with low rates of secondary cardiac risk stratifying tests, especially in patients with negative CTA findings.
  • Structured management guidelines for post-coronary CTA care are crucial.
  • High adherence (96.2%) to local management recommendations was observed.
Abstract

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