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Published on: August 28, 2018
Secondary cardiac risk stratifying tests after coronary computed tomography angiography in emergency department
Vincent A Verheij1, Jan-Erik Scholtz2, Nandini M Meyersohn2
1Department of Emergency Medicine, Massachusetts General Hospital & Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Insights
Secondary cardiac risk stratifying tests after coronary computed tomography angiography (CTA) in the emergency department are low, particularly for negative CTA results. Structured post-CTA guidelines are essential for appropriate patient management.
Area of Science:
- Cardiology
- Radiology
- Emergency Medicine
Background:
- Coronary computed tomography angiography (CTA) in triage strategies has shown increased secondary cardiac risk stratifying tests (SCRSTs).
- The impact of CTA on SCRSTs in routine emergency department (ED) clinical care is not well-established.
- This study investigates SCRST rates following the implementation of coronary CTA in an ED setting.
Purpose of the Study:
- To evaluate the rates of secondary cardiac risk stratifying tests (SCRSTs) after coronary CTA in routine clinical practice.
- To determine if SCRST rates vary based on coronary CTA results (positive, intermediate, negative, non-diagnostic).
- To assess adherence to local management recommendations for post-CTA diagnostic strategies.
Main Methods:
- A single-site retrospective cohort study of ED patients who received coronary CTA between October 1, 2012, and September 30, 2016.
- SCRSTs included functional cardiac tests and invasive coronary angiography (ICA).
- Data analysis focused on CTA results and the performance of subsequent SCRSTs.
Main Results:
- Out of 1916 patients, 9.3% had positive, 5.5% intermediate, 84.1% negative, and 1.1% non-diagnostic CTAs.
- Overall SCRST rate was 12.4% (5.6% noninvasive, 6.7% ICA).
- SCRST rates were high after positive (73.7%) and intermediate (72.4%) CTAs, but low after negative (1.1%) and non-diagnostic (47.6%) CTAs.
Conclusions:
- Routine emergency department coronary CTA is associated with low rates of secondary cardiac risk stratifying tests, especially in patients with negative CTA findings.
- Structured management guidelines for post-coronary CTA care are crucial.
- High adherence (96.2%) to local management recommendations was observed.
Background:
Several large trials demonstrated that coronary computed tomography angiography (CTA) in a triage strategy could lead to increased secondary cardiac risk stratifying testing (SCRST). Whether this is true for routine clinical care remains unclear. We measured SCRSTs after coronary CTA was implemented in our emergency department (ED) practice by CTA result, and if locally existing management recommendations for a structured post CTA diagnostic strategy were followed.
Methods:
This single site retrospective cohort study included all our ED patients who received coronary CTA between October 1, 2012 and September 30, 2016. SCRST's included functional cardiac tests and invasive coronary angiography (ICA), performed during the ED coronary CTA visit or related admission.
Results:
A total of 1916 subjects were included with a mean age of 52.9 ± 10.8 years. Of their coronary CTAs, 179 were positive (severe stenosis, occlusion or ventricular wall motion abnormalities; 9.3%), 105 intermediate (moderate stenosis; 5.5%), 1611 negative (no to mild obstructive CAD; 84.1%) and 21 non-diagnostic (1.1%). SCRSTs were performed in 237 (overall 12.4%, noninvasive in 5.6%, ICA in 6.7%). After positive coronary CTA, 73.7% of subjects received SCRSTs. For intermediate, negative and non-diagnostic CTAs this was 72.4%, 1.1% and 47.6% respectively. Management conformed to local management recommendations in 96.2% of cases.
Conclusion:
In spite of previous trials, rates of secondary cardiac risk stratifying tests after routine clinical ED coronary CTA are low, especially in patients with negative coronary CTA. Structured management guidelines for post coronary CTA, and adherence to these guidelines, appear essential.
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