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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Amide proton transfer imaging of tumors: theory, clinical applications, pitfalls, and future directions
Kiyohisa Kamimura1, Masanori Nakajo2, Tomohide Yoneyama2
1Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan. kiyohisa@m2.kufm.kagoshima-u.ac.jp.
Abstract:
Amide proton transfer (APT) imaging is an emerging molecular magnetic resonance imaging technique based on chemical exchange saturation transfer (CEST). APT imaging has shown promise in oncologic imaging, especially in the imaging of brain tumors. This review article illustrates the theory of CEST/APT imaging and describes the clinical utility, pitfalls, and potential for future development of APT imaging.
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