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Published on: February 16, 2011
Study of Rhythm Disturbances in Acute Myocardial Infarction
1Professor, JNMC, Sawangi Wardha, Maharashtra; *Corresponding Author.
Insights
Cardiac rhythm disturbances are common in acute myocardial infarction (AMI). This study found sinus tachycardia and bradycardia were the most frequent arrhythmias, with tachyarrhythmias leading to significantly higher mortality in AMI patients.
Area of Science:
- Cardiology
- Clinical Medicine
- Arrhythmology
Background:
- Cardiac rhythm disturbances are frequent complications of acute myocardial infarction (AMI).
- Early reperfusion therapy has reduced AMI mortality, but arrhythmias remain critical events.
- Limited data exists on rhythm disturbances in AMI patients from rural central India.
Purpose of the Study:
- To investigate the types of rhythm disturbances in acute myocardial infarction (AMI).
- To correlate arrhythmias with the clinical profile of AMI patients.
- To assess the impact of arrhythmias on AMI outcomes in a rural tertiary care setting.
Main Methods:
- Retrospective analysis of acute ST-elevation and non-ST-elevation MI patients with rhythm disturbances.
- Data collected from April 2012 to 2014 during reperfusion therapy or ICU stay.
- Focus on patient demographics, clinical presentation, risk factors, and arrhythmia types.
Main Results:
- Sinus tachycardia (86%) and sinus bradycardia (68%) were the most common arrhythmias.
- Hypertension was the most frequent risk factor; chest pain (97%) and palpitations (63%) were common symptoms.
- Mortality was significantly higher in patients with tachyarrhythmias (55.71% in AWMI, 17.14% in IWMI) compared to bradyarrhythmias (p < 0.0001).
Conclusions:
- Sinus tachycardia and bradycardia are the predominant arrhythmias in this AMI cohort, differing from global findings where atrial fibrillation is more common.
- Tachyarrhythmias are associated with significantly increased mortality in acute myocardial infarction.
- Findings highlight the specific arrhythmia profile and outcomes in a rural Indian AMI population.
Introduction:
Cardiac rhythm disturbances are common presentation in acute coronary syndromes and are cause of frequent serious complications in acute myocardial infarction (AMI). However due to availability of early reperfusion therapy and primary angioplasty, arrhythmias have cause a reduction in mortality. Arrhythmias are key events before, during or after the occurrence of acute MI. There are few clinical studies describing the types of arryhthmias, their correlation with the clinical profile of acute MI and effect on outcomes. In rural tertiary care centre, patients of acute MI, receive reperfusion therapy. The Indian population from central India is mostly a farming community from rural areas with limited medical aid resources. A tertiary care centre can only provide early reperfusion therapy in acute MI. There is very little data on rhythm disturbances in acute myocardial infarction from this geographic region.
Objectives:
To study rhythm disturbances in acute myocardial infarction(AMI) and its effect on outcome.
Methods:
All cases of acute ST elevation and non ST elevation MI having rhythm disturbances during reperfusion or ICU stay admitted between April 2012 to 2014.
Results:
Rhythm disturbances were seen in 40-69 years of age. Chest pain (97%) and palpitation (63%) were commonest complaints. Hypertension was commonest risk factor. Sinus tachycardia (86%),ventricular ectopics (17%) and ventricular tachycardia (16%) were commonest tachyarrhythmias and sinus bradycardia (68%), right (23%) and left (18%)bundle branch blocks commonest bradyarrhythmias. Mortality was higher in tachyarrhythmias.
Conclusion:
Compared to studies elsewhere it was observed that sinus tachycardia and bradycardia were commonest arrhythmias in AMI. That atrial fibrillation as observed in most studies elsewhere was not a common arrhythmia in this study. Mortality was statistically significant in tachyarrhythmias in both AWMI(55.71%) and IWMI(17.14%) as compared to bradyarrhythmias with p < 0.0001.
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