A novel semiconductor based wireless electrochemical sensing platform for chronic disease management

Electrochemical sensors are very versatile and can be used for a diverse range of biomedical applications. In this paper, a novel fully-integrated wireless electrochemical sensing platform is presented. The platform uses standard semiconductor technology to create a miniaturized integrated bioelectronics system that consists of an electrochemical sensor, potentiostat, signal processing circuitry, wireless power harvesting circuitry, and wireless telemetry unit, all on a single microchip. The platform is orders of magnitude smaller than the state-of-the-art sensing systems and costs a fraction. At 1.4 mm × 1.4 mm size, the sensor costs less than $1 to manufacture. The presented design provides fundamental advantages in decreasing sensor noise and settling time, thus providing superior response compared to existing solutions. System design and implementation details are presented as well as examples for metabolic sensing (glucose, lactate, O₂) applications. The system can have widespread applications in biosensing applications.