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Updated: Feb 3, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[PR-EMPTIVE TREATMENT FOR HYPEREMESIS GRAVIDARUM]
Rana Cohen1, Gideon Koren1,2
1Motherisk Israel, Clinical Pharmacology Unit, Assaf Harofe Hospital.
Background:
Hyperemesis gravidarum (HG) affects around 1% of pregnant women. The experience is traumatic, and many women hesitate to start a subsequent pregnancy in view of the tendency of HG to re-occur.
Objectives:
A 25 year old woman who experienced HG in her previous pregnancy was very afraid to start a second pregnancy, as she considered the termination of the first, traumatic pregnancy. She was advised to use pre- emptive antiemetic therapy with an anti emetic drug before any symptom appeared. The pregnancy passed with only mild nausea and vomiting.
Discussion:
Several controlled randomized studies have shown the effectiveness of pre emptive therapy in preventing a repeat of HG symptoms.
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