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Genetic Markers for Coronary Artery Disease
Nevena Veljkovic1, Bozidarka Zaric2, Ilona Djuric3
1Centre for Multidisciplinary Research and Engineering, Institute of Nuclear Science Vinca, University of Belgrade, 11000 Belgrade, Serbia. nevenav@vin.bg.ac.rs.
Medicina (Kaunas, Lithuania)
|October 23, 2018
Summary
Genetic factors significantly influence coronary artery disease (CAD) and myocardial infarction (MI) risk. Research between 2003-2018 highlights genetic markers for CAD, potentially aiding clinical risk assessment with advancing genetic testing.
Area of Science:
- Cardiovascular Medicine
- Genetics
- Public Health
Background:
- Coronary artery disease (CAD) and myocardial infarction (MI) are primary causes of death globally.
- While lifestyle factors are known contributors, genetic predisposition plays a significant role in these vascular conditions.
Purpose of the Study:
- To review existing literature on genetic markers associated with CAD.
- To assess the potential clinical utility of genetic markers for risk stratification.
Main Methods:
- Systematic review of English and non-English articles with English abstracts.
- Literature search focused on genetic markers for CAD published between 2003 and 2018.
Main Results:
- The review identified various genetic markers linked to CAD.
- Data suggests a growing body of evidence supporting genetic influences on CAD development.
Conclusions:
- Genetic background is a crucial factor in CAD and MI.
- Genetic testing may offer a valuable tool for identifying individuals at high risk for CAD in clinical practice.
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