Related Experiment Video
Updated: Feb 3, 2026
10:53
Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
5.9K
Myocardial fibrosis
Summary
Myokardfibrose, arrdannelse i hjertemuskelen, kan svekke hjertefunksjonen og forverre prognosen. Ny diagnostikk forbedrer påvisning, og forskning fokuserer på å utvikle medisiner for å bremse eller reversere fibrose.
Area of Science:
- Cardiology
- Pathology
- Biomedical Research
Background:
- Myocardial fibrosis develops secondary to cardiac stress or injury.
- This review covers key aspects of myocardial fibrosis.
Purpose of the Study:
- To review current understanding and diagnostic approaches to myocardial fibrosis.
- To highlight the prognostic implications and therapeutic targets for myocardial fibrosis.
Main Methods:
- A systematic literature search was conducted in PubMed.
- Two searches yielded 417 articles; 44 were selected based on relevance.
- Analysis included title, abstract, and full-text review.
Main Results:
- Myocardial fibrosis is classified as interstitial or replacement fibrosis.
- Fibrosis can negatively impact cardiac electrical and mechanical function, worsening prognosis.
- Advanced imaging and biomarker research have improved fibrosis detection.
Conclusions:
- Modern diagnostics enhance the detection and understanding of myocardial fibrosis in heart disease.
- Developing antifibrotic medications holds significant potential for cardiovascular medicine.
Related Concept Videos
01:23Cystic Fibrosis: Pathogenesis
874
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
874
01:24Cystic Fibrosis: Management
541
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
541
01:47Lung Capacity
56.3K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.3K