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[Ecthyma gangrenosum].

Ahlam Abdou1, Badredine Hassam1

  • 1University Mohammed V, Ibn Sina, Hospital University, Rabat, Morocco.

The Pan African Medical Journal
|October 23, 2018
PubMed
Summary
This summary is machine-generated.

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Ecthyma gangrenosum is a severe skin infection typically seen in immunocompromised individuals. Prompt antibiotic treatment, as demonstrated in a pediatric case, leads to complete recovery.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pediatrics

Background:

  • Ecthyma gangrenosum (EG) is a serious, potentially fatal skin infection characterized by a progression from rash to necrotic ulcers.
  • EG primarily affects immunocompromised patients, including those with neutropenia, HIV, or undergoing chemotherapy.
  • Differential diagnoses for EG include leishmaniasis, pyoderma gangrenosum, and papulonecrotic tuberculides.

Observation:

  • A 2-year-old child with no prior medical history presented with multiple necrotic ulcers and fever.
  • Initial blood cultures were negative, but pus samples identified Pseudomonas aeruginosa as the causative agent.
  • Inflammatory markers, including sedimentation rate and C-reactive protein, were elevated.

Findings:

  • The patient was diagnosed with ecthyma gangrenosum (EG).
Keywords:
Pseudomonaschildecthyma

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  • Treatment involved parenteral administration of third-generation cephalosporins based on susceptibility testing.
  • The child experienced complete recovery and wound healing within four weeks.

    • Implications:

    • This case highlights the importance of prompt diagnosis and appropriate antibiotic therapy for ecthyma gangrenosum, even in seemingly healthy children.
    • Early intervention with targeted antibiotics can lead to favorable outcomes in severe cutaneous infections.
    • Pseudomonas aeruginosa remains a significant pathogen in ecthyma gangrenosum, necessitating effective antimicrobial strategies.