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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
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Supporting general practitioner-based care for poorly controlled type 2 diabetes mellitus (the DECIDE study):
Mark E Murphy1, Molly Byrne2, Fiona Boland1
11HRB Centre for Primary Care Research, Royal College of Surgeons, Dublin, Ireland.
Pilot and Feasibility Studies
|October 23, 2018
Summary
This pilot study will assess the feasibility of the DECIDE intervention to improve type 2 diabetes mellitus management in Irish general practice. The goal is to reduce clinical inertia and enhance patient outcomes through decision support.
Area of Science:
- Primary care research
- Clinical decision support systems
- Diabetes mellitus management
Background:
- Poorly controlled type 2 diabetes mellitus (T2DM) presents significant health challenges and costs.
- Clinical inertia, a barrier to intensifying treatment, complicates T2DM management.
- The DECIDE intervention was developed to support therapeutic action in T2DM care.
Purpose of the Study:
- To present the protocol for a pilot cluster randomized controlled trial (RCT) of the DECIDE intervention.
- To evaluate the feasibility of implementing a complex intervention in Irish General Practice for T2DM.
- To address clinical inertia and improve glycaemic and blood pressure control in T2DM patients.
Main Methods:
- A pilot cluster RCT involving 14 general practices and 140 patients with poorly controlled T2DM (HbA1c > 70 mmol/mol and/or BP > 150/95).
- Intervention group receives the DECIDE intervention: training and a web-based clinical decision support system.
- Control group receives usual care; primary outcomes focus on feasibility (recruitment, retention, acceptability) and HbA1c.
Main Results:
- Feasibility outcomes including recruitment and retention rates will be assessed.
- Acceptability of the DECIDE intervention among general practitioners and patients will be evaluated.
- Changes in HbA1c, blood pressure, and medication intensification will be secondary outcomes.
Conclusions:
- The pilot cluster RCT will establish the feasibility of the DECIDE intervention.
- Findings will inform the design of a larger trial to improve primary care for T2DM.
- The study aims to support healthcare professionals in managing poorly controlled T2DM effectively.
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