Related Experiment Video
Updated: Feb 3, 2026

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals
Published on: March 13, 2011
Origin of the Autophagosome Membrane in Mammals
Yun Wei1, Meixia Liu1, Xianxiao Li2
1Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Abstract:
Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-membrane autophagosomes. Autophagosomes ultimately fuse with lysosomes, where the cytosolic cargoes are degraded. Accumulation of autophagosomes is a hallmark of autophagy and neurodegenerative disorders including Alzheimer's and Huntington's disease. In recent years, the sources of autophagosome membrane have attracted a great deal of interests, even so, the membrane donors for autophagosomes are still under debate. In this review, we describe the probable sources of autophagosome membrane.
Related Concept Videos
Cancers Originate from Somatic Mutations in a Single Cell
Introduction to Membrane Proteins
What are Membranes?
What are Membranes?
The Resting Membrane Potential
Membrane Fluidity

