CRISPR-Cas9/Cas12a biotechnology and application in bacteria

Ruilian Yao1, Di Liu2, Xiao Jia1

  • 1State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.

Summary

CRISPR-Cas technologies, including CRISPR-Cas9 and CRISPR-Cas12a, offer powerful tools for genome editing, gene regulation, and nucleic acid detection. These advancements are revolutionizing synthetic biology and metabolic engineering in bacteria.

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