RANDOMIZED CLINICAL TRIAL OF AN INTERNET-BASED INTERVENTION TO PREVENT ADOLESCENT DEPRESSION IN A PRIMARY CARE...

We developed and tested two primary care based approaches for the early identification and prevention of depressive disorders in adolescents. We conducted a randomized controlled trial originally intended to compare Brief Advice (BA) + Internet intervention with Motivational Interviewing (MI) + Internet intervention in primary care for adolescents experiencing persistent subthreshold depression (Project CATCH-IT). This is an exploratory long-term 2.5 year follow-up study of a phase II study comparing pre/post outcomes and potential moderators of outcomes. Participants (n=44) in the entire cohort maintained from baseline and continued to reduce depressive symptoms and percentage of subsyndromal depression. Greater motivation for depression prevention and lower ratings of self-efficacy at baseline were associated with greater declines in depression symptoms. These results suggest adolescents can be followed-up after Internet studies and there may be evidence of sustained reductions in depressed mood. The CATCH-IT model offers the possibility of a long term effect, but these results are limited by the small sample size and pre-post design. A large scale randomized clinical trial of the intervention is currently in progress.