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Related Experiment Video

Updated: Feb 3, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Moisturizers: A Comparison Based on Allergens and Economic Value.

Margaret Chou1, Daniela Mikhaylov, Tamara Lazic Strugar

  • 1From the Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY.

Dermatitis : Contact, Atopic, Occupational, Drug
|October 23, 2018
PubMed
Summary
This summary is machine-generated.

Expensive moisturizers may contain more allergens than cheaper alternatives. This study found higher average allergen counts in pricier cosmetic products, suggesting cost doesn't indicate safety for allergic contact dermatitis (ACD).

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Area of Science:

  • Dermatology
  • Cosmetic Science
  • Allergology

Background:

  • The increasing economic impact of cosmetic products like moisturizers necessitates research into their safety.
  • Despite high market prices, the allergenicity of many moisturizers remains unstudied.

Purpose of the Study:

  • To investigate potential allergens in moisturizers across different price points.
  • To analyze ingredients of online moisturizers from CVS Health, comparing expensive and inexpensive options.

Main Methods:

  • A cross-sectional study analyzed 100 moisturizers (50 expensive, 50 inexpensive) from CVS Health.
  • Ingredients were cross-referenced with known sensitizers from the American Contact Dermatitis Society and North American Contact Dermatitis Group.
  • Statistical analysis (t-tests, chi-squared/Fisher exact tests) compared allergen counts and groups.

Main Results:

  • A total of 26 allergenic substances were identified across the surveyed products.
  • Expensive moisturizers contained a significantly higher average number of allergens (8.28) compared to inexpensive ones (5.60).

Conclusions:

  • Higher-priced moisturizers may pose a greater risk for allergic contact dermatitis (ACD).
  • Physicians should advise patients that product cost is not a reliable indicator of ACD risk.