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Updated: Aug 19, 2026

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice
Published on: September 17, 2015
[Regional changes in circulation in response to stimulation of beta-adrenergic receptors with isoproterenol]
Abstract:
The muscle and adrenal fractions of cardiac output increased after injection of isoproterenol. The relative blood flow increase in skeletal muscles was accompanied with the increase in regional by-pass blood flow. The latter or reduction in the vessel permeability were found in the lungs. The cardiac output fractions decreased in extensive areas of skin, brain, myocardium, internal organs of hepatic portal vein, kidneys, testicles. The signs of the blood flow increase were found in the brain, myocardium, liver. The relative blood volume decreased in the majority of internal organs and tissues while increasing in the liver.
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