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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
Published on: May 10, 2018
The German version of the Functional Walking Categories (FWC): translation and initial validation
Susanne G R Klotz1,2, Corinna Petersen-Ewert3, Gesche Ketels2
1a Department of Health Sciences , Hamburg University of Applied Sciences , Hamburg , Germany.
Background:
Community ambulation is often affected after a stroke. However, no validated assessment in German to measure community ambulation on a participation level exists.
Objectives:
The purpose was to translate and cross-culturally adapt the Functional Walking Categories (FWC) into German and to assess its validity and reliability in patients with stroke.
Methods:
Cross-cultural adaptation guidelines were used for translation. Face and content validity were established with the aid of an expert committee. A pilot study with patients after stroke in a neurological rehabilitation setting checked for concurrent validity using Kendall's tau and reliability using intraclass correlation coefficients.
Results:
The results indicated that the German version of the FWC has adequate face and content validity. A total of 30 patients (mean age 62 ± 12.315 years, 56.7% female) participated in the study. The FWC correlated well with the Functional Ambulation Categories (tau-b = 0.783), cadence (tau-b = 0.640), gait velocity (tau-b = 0.628), the comfortable 10-m timed walk (tau-b = -0.629), and the fast 10-m timed walk (tau-b = -0.634). Moderate correlations were found between the FWC and step length (tau-b = 0.483) and the Timed Up and Go (tau-b = -0.520), respectively. Intrarater reliability was moderate (ICC = 0.651) while interrater reliability was excellent (ICC = 0.751) (all correlations p < 0.001). However, the study was designed as pilot study, thus, full psychometric property testing was not possible.
Conclusions:
The German FWC offers a reasonable tool for measuring community ambulation on participation level. However, a user manual seems to be helpful.
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