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A Rare Survival in Celphos Poisoning.
Praveen Kumar P1, M Babu1, Poornima Nair1
1Junior Resident in General Medicine.
The Journal of the Association of Physicians of India
|October 24, 2018
Summary
Aluminium phosphide poisoning causes heart rhythm problems by affecting cellular energy production. This case highlights supraventricular and ventricular tachycardia in celphos poisoning.
Area of Science:
- Toxicology
- Cardiology
- Biochemistry
Background:
- Aluminium phosphide (AlP) poisoning is a significant cause of mortality.
- Phosphine gas (PH3) released from AlP inhibits cellular respiration, specifically cytochrome oxidase and the electron transport chain.
- This leads to myocardial suppression and a range of cardiac electrical abnormalities.
Observation:
- This report details a case of AlP poisoning, also known as celphos poisoning.
- The patient presented with significant cardiac manifestations.
Findings:
- The poisoning resulted in both supraventricular tachycardia (SVT) and ventricular tachycardia (VT).
- These arrhythmias represent severe electrical instability of the myocardium secondary to phosphine toxicity.
Implications:
- This case underscores the critical cardiac risks associated with Aluminium phosphide poisoning.
- Early recognition and management of cardiac arrhythmias are vital in treating AlP toxicity.
- Further research into the specific mechanisms of phosphine-induced cardiotoxicity may improve patient outcomes.
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