Cryptococcal meningitis mimicking cerebral infarction: a case report
Weihua Zhou1,2,3, Jianbo Lai1,2,3, Tingting Huang1
1Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China, dorhushaohua@zju.edu.cn.
Abstract:
Cryptococcal meningitis (CM) is the most common type of fungal meningitis. The clinical symptoms of CM are nonspecific, and neuroimaging characteristics are variable. Herein, we present a case of a senile female with CM that was once misdiagnosed as cerebral infarction. Her condition worsened and she developed hydrocephalus. No apparent predisposing factors of CM were reported in this patient. The diagnosis of CM was definitely made after India ink staining of cerebrospinal fluid was positive. This case indicates that clinicians should bear cryptococcal infection in mind when the symptoms are nonspecific and neuroimaging findings are atypical.
Insights
Cryptococcal meningitis (CM) can mimic other conditions like cerebral infarction, even in elderly patients. Early diagnosis using cerebrospinal fluid analysis is crucial for effective treatment of this serious fungal infection.
Area of Science:
- Neurology
- Infectious Diseases
- Mycology
Background:
- Cryptococcal meningitis (CM) is a significant fungal infection, particularly in immunocompromised individuals.
- Clinical presentation of CM is often nonspecific, posing diagnostic challenges.
- Neuroimaging findings in CM can be variable and atypical.
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