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Updated: Feb 3, 2026

Using the Horseshoe Crab, Limulus Polyphemus, in Vision Research
Published on: July 3, 2009
One type of duplex appendix: horseshoe appendix
Jin Liu1, Chengyong Dong2, Haibo Wang2
1General Surgery, Center for New Material and New Precision Technology of Cancer Therapy, Dalian Medical University, Dalian, Liaoning, China, wangbcc259@163.com.
Abstract:
A horseshoe appendix is a subtype of duplex appendix, in which the appendix is shaped like a circle that may lead to an internal hernia and result in intestinal necrosis. This subtype is extremely rare, with only 13 cases reported worldwide to date, and easily triggers a series of medico-legal consequences due to the neglect of another infection base of the appendix. We describe a 22-year-old man who presented with a 3-day history of fever and was diagnosed with pneumonia. After receiving antibiotics for 3 days in the Department of Pneumology, he was found to have a periappendiceal abscess. He underwent appendectomy after 3 days of conservative treatment failure in the Department of General Surgery. During the operation, we found that he had a horseshoe appendix with the two bases forming a circle, each communicating with the cecum. We provide a review of 13 cases presented in the literature, with a discussion of the clinical features, diagnosis, and surgical approach of the horseshoe appendix to make the general surgeon get a clear concept of this type of appendicitis.
Insights
A rare horseshoe appendix, a circular-shaped appendix, can cause internal hernias and intestinal necrosis. This case highlights the importance of recognizing this rare condition to avoid misdiagnosis and ensure timely surgical intervention for appendicitis.
Area of Science:
- Gastroenterology
- Surgical Anatomy
- Medical Case Reports
Background:
- A horseshoe appendix is an extremely rare congenital anomaly, a subtype of duplex appendix, characterized by a circular shape.
- This anatomical variation can predispose individuals to internal hernias and subsequent intestinal necrosis.
- Previous literature reports only 13 cases globally, underscoring its rarity and diagnostic challenges.
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