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Human Thelaziasis: Emerging Ocular Pathogen in Nepal.

Ranjit Sah^1,2, Shusila Khadka¹, Mahesh Adhikari¹

¹Department of Microbiology, Tribhuvan University Teaching Hospital Institute of Medicine, Maharajgunj, Kathmandu, Nepal.

Open Forum Infectious Diseases

|October 24, 2018

Summary

This study reports the first case of human ocular thelaziasis in Nepal, a zoonotic eye infection caused by Thelazia callipaeda nematodes. Symptoms resolved after surgical removal of the worms from a 6-month-old infant.

Keywords:

Nepal Phortica variegata Thelazia callipaeda Thelaziasis zoonotic disease

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Area of Science:

Ophthalmology
Parasitology
Zoonotic Diseases

Background:

Thelaziasis is an arthropod-borne zoonotic disease affecting the eye.
It is caused by nematodes of the genus Thelazia, infecting ocular structures like the conjunctiva and lacrimal system.

Purpose of the Study:

To report the first documented case of human ocular thelaziasis in Nepal.
To identify the causative nematode species and describe the clinical presentation and management.

Main Methods:

Clinical case report of a 6-month-old infant presenting with conjunctivitis.
Surgical removal of nematodes from the affected eye.
Morphological identification of the collected nematodes.

Main Results:

The first case of human ocular thelaziasis in Nepal is described in a 6-month-old child.
Six Thelazia callipaeda nematodes were removed from the patient's conjunctival sac.
The infant's symptoms, including conjunctivitis, resolved post-worm removal.

Conclusions:

Thelazia callipaeda can cause ocular infections in humans in Nepal.
Prompt diagnosis and surgical removal are effective treatments for ocular thelaziasis.
This case highlights the importance of recognizing zoonotic diseases in pediatric ophthalmology.