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Copper-Mediated C-H Amination of Imidazopyridines with N-Fluorobenzenesulfonimide

Shuai Lu1, Lu-Lu Tian1, Tian-Wei Cui1

  • 1College of Chemistry and Molecular Engineering , Zhengzhou University , No. 100 Science Road , Zhengzhou , Henan 450001 , P. R. China.

The Journal of Organic Chemistry
|October 24, 2018
PubMed

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Alkylation is one of the methods used to prepare amines. Direct alkylation of ammonia or a primary amine with an alkyl halide gives polyalkylated amines along with a quaternary ammonium salt through successive SN2 reactions. This process of making the quaternary salt through the direct alkylation method is called exhaustive alkylation.
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