Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

727
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
727
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

1.1K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.1K
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

575
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
575
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

1.3K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.3K
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

631
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
631
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

864
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
864

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of abdominal symptoms and intestinal inflammation in children and adolescents with cystic fibrosis without highly effective modulator therapy.

Jornal de pediatria·2026
Same author

Telehealth - A Clinical Practice Initiative in Pediatrics.

Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners·2026
Same author

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk.

Journal of pediatric gastroenterology and nutrition·2026
Same author

Diet quality in Brazilian adolescents with cystic fibrosis.

Jornal de pediatria·2025
Same author

SMALL INTESTINAL BACTERIAL OVERGROWTH IN PEOPLE WITH CYSTIC FIBROSIS: SYSTEMATIC REVIEW.

Arquivos de gastroenterologia·2025
Same author

Outcomes and factors associated with tolerance in infants with non-IgE-mediated cow's milk allergy with gastrointestinal manifestations.

Jornal de pediatria·2023

Related Experiment Video

Updated: Feb 3, 2026

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
03:20

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease

Published on: September 22, 2023

2.4K

Refractory functional constipation: clinical management or appendicostomy?

Vanesca P A de Arruda1, Maria A Bellomo-Brandão2, Joaquim M Bustorff-Silva3

  • 1Universidade Estadual de Campinas (Unicamp), Faculdade de Ciências Médicas, Campinas, SP, Brazil.

Jornal De Pediatria
|October 24, 2018
PubMed
Summary

Appendicostomy surgery effectively controlled refractory functional constipation and retentive fecal incontinence in children, leading to more spontaneous bowel movements compared to clinical treatment. However, surgical complications were frequent.

Keywords:
AdolescentAdolescenteChildConstipação intestinalCriançaEnemaFecal incontinenceFunctional constipationIncontinência fecal

More Related Videos

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

1.0K
MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.8K

Related Experiment Videos

Last Updated: Feb 3, 2026

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
03:20

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease

Published on: September 22, 2023

2.4K
Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

1.0K
MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.8K

Area of Science:

  • Pediatric Gastroenterology
  • Surgical Interventions
  • Functional Bowel Disorders

Background:

  • Refractory functional constipation is a challenging condition in children, often defined by persistent fecal incontinence despite standard therapies.
  • Antegrade enemas via appendicostomy offer a surgical alternative to traditional rectal enemas for managing severe cases.

Purpose of the Study:

  • To compare the clinical outcomes of pediatric patients with refractory functional constipation treated with either antegrade enemas via appendicostomy or conventional clinical management.
  • To evaluate the efficacy and safety of appendicostomy versus oral laxatives and rectal enemas in achieving fecal continence and spontaneous bowel movements.

Main Methods:

  • A cohort of 28 pediatric patients with refractory functional constipation was analyzed.
  • Patients were divided into two groups: those undergoing appendicostomy for antegrade enemas and those receiving clinical treatment with oral laxatives and rectal enemas.
  • Outcomes including fecal incontinence control and spontaneous evacuations were assessed at 6, 12, and 24 months post-intervention.

Main Results:

  • Appendicostomy significantly improved control of retentive fecal incontinence, with higher rates observed at 6, 12, and 24 months compared to clinical treatment (p<0.001 at 12 months, p=0.005 at 24 months).
  • Operated patients showed a higher frequency of spontaneous bowel movements at final evaluation (9/16 vs. 3/10, p=0.043).
  • Appendicostomy was associated with a high incidence of surgical complications (42 episodes in 14/17 patients).

Conclusions:

  • Appendicostomy provides an effective treatment for refractory functional constipation, achieving earlier and more frequent control of fecal incontinence than clinical management.
  • Despite a high rate of complications, appendicostomy offers a viable option for selected patients, with treatment decisions requiring careful family counseling on risks and benefits.