Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Initiation of Translation02:33

Initiation of Translation

39.0K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.0K
Initiation of Translation02:33

Initiation of Translation

8.1K
8.1K
Uncertainty in Measurement: Accuracy and Precision03:37

Uncertainty in Measurement: Accuracy and Precision

101.2K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
101.2K
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

547
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
547
Data Reporting and Recording01:24

Data Reporting and Recording

5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Transcription Initiation01:47

Transcription Initiation

21.0K
Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...
21.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Focal Therapy for Prostate Cancer: A Treatment Option Reserved for the Ideal Candi-date?

International braz j urol : official journal of the Brazilian Society of Urology·2026
Same author

Oncological Outcomes Following Focal HIFU and Cryotherapy for Treatment of Nonmetastatic Prostate Cancer in the United Kingdom: An Updated Analysis of 3477 Patients from the Prospective HEAT and ICE Registries.

European urology·2026
Same author

Impact of prostate mpMRI quality on diagnostic accuracy in prostate cancer: a prospective study.

BJU international·2026
Same author

ProBIOPSY: A Multidisciplinary International Consensus on Standards for Prostate Biopsy.

European urology·2026
Same author

Focal Therapy for Localized Prostate Cancer: Maturing Evidence, Evolving Questions.

European urology·2026
Same author

Temporal Trends of Metastatic Prostate Cancer in the Prostate-Specific Membrane Antigen Positron Emission Tomography Era in the United States.

The Prostate·2026

Related Experiment Video

Updated: Feb 3, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

846

Sequential prostate MRI reporting in men on active surveillance: initial experience of a dedicated PRECISE software

Francesco Giganti1, Clare Allen2, Jonathan W Piper3

  • 1Department of Radiology, University College London Hospital NHS, Foundation Trust, London, UK; Division of Surgery & Interventional Science, University College London, London, UK.

Magnetic Resonance Imaging
|October 24, 2018
PubMed
Summary

A new software tool streamlines prostate cancer active surveillance by automating multiparametric MRI comparisons, significantly reducing radiologist reporting time for sequential scans.

Keywords:
Active surveillanceComputer-aided diagnosisMagnetic resonance imagingProstatic neoplasms

More Related Videos

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

22.4K
Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software
08:57

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Published on: September 4, 2021

4.5K

Related Experiment Videos

Last Updated: Feb 3, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

846
Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

22.4K
Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software
08:57

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Published on: September 4, 2021

4.5K

Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Sequential multiparametric MRI (mpMRI) is crucial for monitoring prostate cancer patients on active surveillance (AS).
  • Current standardized reporting (PRECISE recommendations) requires time-consuming manual lesion size measurements.
  • There is a need for efficient tools to systematically report serial mpMRI scans.

Purpose of the Study:

  • To validate a dedicated software tool for automated comparison of sequential mpMRI scans in men undergoing AS.
  • To assess the impact of the PRECISE reporting software on radiologist reporting time.

Main Methods:

  • Retrospective analysis of 20 men (dutasteride vs. placebo) from the MAPPED trial.
  • Comparison of reporting times and lesion assessments using commercial software (Osirix®) versus a semi-automated PRECISE tool (MIM®).
  • Assessment of tumour volume and diffusion-weighted imaging conspicuity; statistical analysis using the Wilcoxon test.

Main Results:

  • Tumour volumes and conspicuity were comparable between the two reporting methods.
  • The PRECISE reporting tool significantly reduced follow-up scan reporting time (p=0.005).
  • Structured reports with comparison tables were generated, adhering to PRECISE recommendations.

Conclusions:

  • A dedicated PRECISE reporting tool significantly decreases reporting time for sequential mpMRI in prostate cancer AS.
  • This software facilitates easier comparison of scans over time, aiding understanding of disease progression.
  • The tool supports systematic reporting and enhances the monitoring of men on active surveillance.