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Radiologic changes in the aging nasal cavity.

Kimia G Ganjaei1, Zachary M Soler2, Elliott D Mappus2

  • 1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC; Rutgers Robert Wood Johnson Medical School, Piscataway, NJ United States.

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Summary
This summary is machine-generated.

Aging increases nasal cavity volume and decreases cribriform plate (CP) bone density. These age-related anatomic changes in the nasal cavity and CP warrant further clinical investigation.

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Area of Science:

  • Anatomy
  • Radiology
  • Gerontology

Background:

  • Understanding age-related changes in the nasal cavity and cribriform plate (CP) is crucial due to an aging global population.
  • These anatomical variations may have significant clinical implications.

Purpose of the Study:

  • To investigate age-related anatomical differences in the nasal cavity and cribriform plate (CP).
  • To correlate computed tomography (CT) findings with age and manual measurements.

Main Methods:

  • Computed tomography (CT) scans from young (18-34 years) and older adult (80-99 years) cohorts were analyzed.
  • Intranasal airspace volumes and CP bony anatomy were manually segmented and assessed for Hounsfield Units (HU) and olfactory foramina.
  • Deformation-based morphometry (DBM) was employed and correlated with manual measurements.

Main Results:

  • Nasal cavity volumes increased significantly (17-75%) with age, with age being the primary influencing factor.
  • Mean HU of the CP showed a negative correlation with age, indicating bone density loss.
  • No age-related differences in olfactory foramina bone stenosis were observed.

Conclusions:

  • Older individuals exhibit increased intranasal volumes and diffuse bone density loss in the CP.
  • Further research is needed to determine the clinical impact of these age-related anatomical alterations in the nasal cavity and CP.