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Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review
Rada Miskovic1,2, Aleksandra Plavsic3,4, Jasna Bolpacic3,4
1Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia. rada_delic@hotmail.com.
Rheumatology International
|October 25, 2018
Summary
This case report details a rare association between severe strongyloidiasis and polyarteritis nodosa. Despite successful treatment for strongyloidiasis, the patient succumbed to complicated pulmonary tuberculosis.
Area of Science:
- Infectious Diseases
- Rheumatology
- Gastroenterology
Background:
- The association between strongyloidiasis and systemic vasculitis is infrequently documented.
- Polyarteritis nodosa is a rare systemic vasculitis that can affect various organs.
Observation:
- A patient presented with severe strongyloidiasis confirmed by parasitic identification in gastrointestinal biopsies and stool.
- Angiography revealed findings consistent with polyarteritis nodosa in the affected patient.
Findings:
- Treatment with albendazole, ivermectin, and corticosteroid withdrawal resolved strongyloidiasis symptoms, with negative stool samples for Strongyloides stercoralis.
- The patient's clinical course was complicated by the development of pulmonary tuberculosis, which proved fatal despite treatment.
Implications:
- This case highlights the potential, though rare, link between strongyloidiasis and systemic vasculitis.
- The occurrence of opportunistic infections like tuberculosis in immunocompromised patients with strongyloidiasis warrants careful monitoring.
Keywords:
CorticosteroidsPolyarteritis nodosaStrongyloides stercoralisStrongyloidiasisSystemic vasculitisTuberculosisMore Related Videos
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