Related Experiment Video
Updated: Feb 3, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
Living Well: An Intervention to Improve Medical Illness Self-Management Among Individuals With Serious Mental Illness
Anjana Muralidharan1, Clayton H Brown1, Jason E Peer1
1Mental Illness, Research, Education and Clinical Center (MIRECC), Veterans Affairs (VA) Capitol Health Care Network (Veterans Integrated Service Network [VISN] 5), Baltimore (Muralidharan, Brown, Klingaman, Hack, Walsh, Goldberg); Division of Psychiatric Services Research, Department of Psychiatry (Muralidharan, Klingaman, Li, Goldberg), and Department of Epidemiology and Public Health (Brown), all at University of Maryland School of Medicine, Baltimore; VA Maryland Healthcare System, Baltimore (Peer); University of Maryland School of Social Work, Baltimore (Hack).
Objective:
Many adults with serious mental illness have significant medical illness burden and poor illness self-management. In this study, the authors examined Living Well, a group-based illness self-management intervention for adults with serious mental illness that was cofacilitated by two providers, one of whom has lived experience with co-occurring mental health and medical conditions.
Methods:
Adults with serious mental illness (N=242) were randomly assigned to Living Well or an active control condition. Participants completed assessments of quality of life; health attitudes; self-management behaviors; and symptoms at baseline, posttreatment, and follow-up. Emergency room use was assessed by means of chart review. Mixed-effects models examined group × time interactions on outcomes.
Results:
Compared with the control group, adults in Living Well had greater improvements at posttreatment in mental health-related quality of life (t=2.15, p=.032), self-management self-efficacy (t=4.10, p<.001), patient activation (t=2.08, p=.038), internal health locus of control (t=2.01, p=.045), behavioral and cognitive symptom management (t=2.77, p=.006), and overall psychiatric symptoms (t=-2.02, p=.044); they had greater improvements at follow-up in physical activity-related self-management (t=2.55, p=.011) and relationship quality (t=-2.45, p=.015). No effects were found for emergency room use. The control group exhibited greater increases in physical health-related quality of life at posttreatment (t=-2.23, p=.026). Significant group differences in self-management self-efficacy (t=2.86,p=.004) and behavioral and cognitive symptom management (t=2.08, p= .038) were maintained at follow-up.
Conclusions:
Compared with an active control group, a peer-cofacilitated illness self-management group was more effective in improving quality of life and self-management self-efficacy among adults with serious mental illness.
More Related Videos
Related Concept Videos
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Concepts of Health and Illness
Dimensions of Health and Illness
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
Models of Health Promotion and Illness Prevention I
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...

