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Updated: Feb 3, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Platinum(II) Terpyridine Complex That Switches Its Photochemical Reactivity in Response to Its Chromic Behavior in
Kentaro Tashiro1, Hiroyoshi Ohtsu2, Masaki Kawano2
1International Center for Materials Nanoarchitectonics , National Institute for Materials Science , 1-1 Namiki , Tsukuba, Ibaraki 305-0044 , Japan.
Abstract:
A platinum(II) terpyridine complex having an enantiopure lactate anion afforded hydrated crystals l- or d-1hyd containing infinite chains of interacting Pt centers, while their dehydration induced crystal-to-crystal transformation into l- or d-1dehyd, respectively, exhibiting less significant Pt-Pt and/or ligand-ligand interactions. That transformation was accompanied by changes in the color as well as the photochemical reactivity of the crystals, where l-1dehyd showed higher reactivity than l-1hyd in the presence of amines under visible-light irradiation.
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