Decline in the Severity of Carotid Atherosclerosis and Associated Risk Factors From 2002 to 2014
Daniel G Hackam1,2,3,4, J David Spence1,2,3
1From the Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute (D.G.H., J.D.S.), Western University, London, Ontario, Canada.
Abstract:
Background and Purpose- Several recent studies suggest declining rates of carotid revascularization for patients with carotid stenosis. We investigated whether carotid atherosclerosis severity has declined in recent years. Methods- We used carotid ultrasound to evaluate stenosis and plaque area in 6039 patients presenting to vascular medicine clinics in 3 eras: 2002 to 2005, 2006 to 2009, and 2010 to 2014. Results- The total plaque area at the time of referral to the clinics declined by 24% between 2002 and 2014; the percentage of patients presenting with carotid stenosis >60% declined by 29.9%, and the number presenting with >80% stenosis declined by 36.4%. There were significant reductions in plasma lipids and blood pressure during the same interval. Conclusions- Atherosclerosis severity seems to be declining over time. Better treatment of risk factors in the community may be responsible.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Magnetic Declination
Conservation of Declining Populations
Atherosclerosis III: Management
Atherosclerosis I: Introduction
Relative Risk


