Related Experiment Video
Updated: Feb 3, 2026

07:48
Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells
Published on: October 9, 2013
21.4K
Sonoelastography of retroareolar carcinomas
Romuald Ferre1, Benoit Mesurolle1
1Cedar Breast Clinic, McGill University Health Center, Royal Victoria Hospital, 687 Pine Ave West, Montreal, PQ H3H 1A1, Canada.
Journal of Gynecology Obstetrics and Human Reproduction
|October 26, 2018
Summary
Retroareolar carcinomas show malignant features on ultrasound and elastography. However, adding elastography to breast ultrasound did not improve diagnostic accuracy in this specific location.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Retroareolar carcinomas are challenging to diagnose due to their location.
- Conventional ultrasound (US) and elastography are imaging modalities used for breast lesion assessment.
Purpose of the Study:
- To review the sonographic and elastographic features of retroareolar carcinomas.
- To evaluate the added diagnostic value of strain elastography in retroareolar lesions.
Main Methods:
- Retrospective analysis of 30 retroareolar carcinomas diagnosed via sonographically guided biopsy.
- Conventional US and strain elastography (using Tsukuba score) were performed prior to biopsy.
- Imaging features were analyzed by two radiologists.
Main Results:
- Most retroareolar carcinomas appeared as hypoechoic masses with irregular shape, non-circumscribed margins, and posterior attenuation.
- The majority were categorized as BI-RADS category 5.
- Approximately half of the lesions appeared firm and larger on strain elastography, consistent with malignancy.
Conclusions:
- Retroareolar carcinomas exhibit characteristic malignant features on US and elastography.
- In this study, strain elastography did not enhance the diagnostic accuracy of breast US for retroareolar lesions.

