Lymph nodes go with the flow

Rafael S Czepielewski1, Gwendalyn J Randolph2

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.

In this issue, Bovay et al. (https://doi.org/10.1084/jem.20180217) invoke a compelling model of interplay between the venous and lymphatic vasculature in regulating the developmental genesis and early expansion of LNs. This work supports an emerging model that lymph-venous crosstalk supports LN functionality at all stages.

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