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Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Validation of the COPD Assessment Test (CAT) in patients with idiopathic pulmonary fibrosis
Heidi Kjeldgaard Grufstedt1, Saher Burhan Shaker1, Hanne Konradsen2
1Department of Respiratory Medicine, Gentofte University Hospital, Hellerup, Denmark.
Introduction:
Idiopathic pulmonary fibrosis (IPF) is a chronic disease with high morbidity and mortality. A reliable and manageable questionnaire that assesses patients' quality of life is needed to help to improve the content of clinical consultations. The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is used in clinical practice; therefore, the aim of this study was to investigate correlations among the CAT, St. George's Respiratory Questionnaire (SGRQ) and clinical parameters among patients diagnosed with IPF. Methods: A retrospective cohort design was employed in which 87 patients diagnosed with IPF who were receiving treatment at an outpatient clinic were included. Results: The CAT was found to be significantly correlated with SGRQ (p < 0.001). Furthermore, the CAT was significantly correlated with all of the included physiological variables. Conclusions: This add to support the validity of the COPD Assessment test (CAT) as a measure of symptoms in patients with IPF which in clinical practice in combination with dialogue between healthcare professionals and the patient, can help to improve the content of a clinical consultation.
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