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Updated: Feb 3, 2026

Small Bowel Transplantation In Mice
Published on: August 20, 2007
Angry bowels breaking hearts: a case series
Youssef Soliman1, Megan Soliman1, Qamar Ahmad1
1Internal Medicine, Rochester General Hospital Rochester, New York, USA.
Insights
Takotsubo cardiomyopathy (TCM) can be triggered by intra-abdominal conditions. This study highlights small bowel obstruction and Clostridium difficile colitis as potential stressors leading to this heart condition.
Area of Science:
- Cardiology
- Gastroenterology
- Internal Medicine
Background:
- Stress cardiomyopathy, or Takotsubo cardiomyopathy (TCM), is characterized by temporary left ventricular dysfunction.
- It typically presents after significant emotional or physical stress, without obstructive coronary artery disease.
Abstract:
Stress cardiomyopathy or Takotsubo cardiomyopathy (TCM) is transient left ventricular apical akinesis in the absence of angiographic evidence of corresponding obstructive coronary artery disease. A classic presentation is of chest pain following intense emotional or physical stress. Reports of stress-inducing triggers include acute respiratory failure, sudden death of a loved one, sympathomimetic drugs, pheochromocytoma crisis, diabetic ketoacidosis, and even earthquakes. We report three cases of intra-abdominal etiologies precipitating Takotsubo cardiomyopathy: two with small bowel obstruction, and one with Clostridium difficile colitis.
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