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Updated: Feb 3, 2026

Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
[HPV-positive oropharyngeal cancer-risk for the partner?]
1Klinik für Hals‑, Nasen‑, Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Ulm, Frauensteige 12, 89070, Ulm, Deutschland. julius-malte.vahl@uniklinik-ulm.de.
Abstract:
A case of HPV-positive, metachronous oropharyngeal cancer in a married couple has been reported in the context of other studies, thus raising the question of whether it is necessary to screen or intensively monitor the partners of patients with HPV-positive oropharyngeal cancer, or whether preventive methods are required. Current data suggests that there is a potential risk for the partner to develop a concordant disease, but because of the lack of consolidated data, no statement on the frequency of this event can presently be made. Further epidemiological trials might be useful.
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