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Related Concept Videos

Subatomic Particles03:37

Subatomic Particles

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Dalton was only partially correct about the particles that make up matter. All matter is composed of atoms, and atoms are composed of three smaller subatomic particles: protons, neutrons, and electrons. These three particles account for the mass and the charge of an atom.
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Electrospray Ionization (ESI) Mass Spectrometry01:12

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Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
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The Nucleosome Core Particle02:10

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Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
The paradox
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The Nucleosome Core Particle01:12

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Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
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2° Amines to N-Nitrosamines: Reaction with NaNO201:20

2° Amines to N-Nitrosamines: Reaction with NaNO2

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Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
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Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision02:43

Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision

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The ideal-gas equation, which is empirical, describes the behavior of gases by establishing relationships between their macroscopic properties. For example, Charles’ law states that volume and temperature are directly related. Gases, therefore, expand when heated at constant pressure. Although gas laws explain how the macroscopic properties change relative to one another, it does not explain the rationale behind it.
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Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
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Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

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Injectable Nanocomposite Hydrogels and Electrosprayed Nano(Micro)Particles for Biomedical Applications.

Nguyen Vu Viet Linh1,2, Nguyen Tien Thinh3,4, Pham Trung Kien1

  • 1Faculty of Materials Technology, Ho Chi Minh City University of Technology (HCMUT), Vietnam National University, Ho Chi Minh City, Vietnam.

Advances in Experimental Medicine and Biology
|October 26, 2018
PubMed
Summary

This study explores advanced polymeric scaffolds, including nanocomposite hydrogels and electrosprayed nanoparticles, for enhanced drug delivery and tissue regeneration. These biomaterials show promise for future clinical applications.

Keywords:
Biomedical applicationsElectrosprayInjectable hydrogelNanocompositePolysaccharide

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3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Regenerative Medicine

Background:

  • Polymeric scaffolds are crucial in biomedical applications, offering capabilities for delivering bioactive components and regenerative cells.
  • These materials are engineered to encapsulate bioactive molecules and nanoparticles, improving tissue regeneration and drug delivery efficacy.

Purpose of the Study:

  • To describe the fabrication, structural characterization, and potential applications of multifunctional nanocomposite hydrogel and polymeric nano(micro)particle-electrosprayed platforms.
  • To highlight the potential of these advanced biomaterials in tissue engineering and drug delivery systems.

Main Methods:

  • Fabrication of multifunctional nanocomposite hydrogel platforms.
  • Development of polymeric nano(micro)particle-electrosprayed platforms.
  • Structural characterization of the developed platforms.

Main Results:

  • Demonstration of multifunctional nanocomposite hydrogel fabrication.
  • Successful creation of polymeric nano(micro)particle-electrosprayed platforms.
  • Characterization of structural properties relevant to biomedical applications.

Conclusions:

  • The described multifunctional nanocomposite biomaterials offer significant potential for tissue regeneration and drug delivery.
  • Further research into these advanced materials could pave the way for their clinical application.
  • These platforms represent a promising direction for the development of next-generation biomedical devices.