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Naturally-Derived Biomaterials for Tissue Engineering Applications.

Matthew Brovold1, Joana I Almeida2, Iris Pla-Palacín2

  • 1Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA.

Advances in Experimental Medicine and Biology
|October 26, 2018
PubMed
Summary
This summary is machine-generated.

Naturally-derived biomaterials are essential in regenerative medicine and tissue engineering. This chapter classifies these materials and explores their applications in drug discovery, developmental biology, bioprinting, and transplantation.

Keywords:
Extracellular matrix-derived biomaterialsGlycosaminoglycansNaturally-derived materialsPolysaccharide-based biomaterialsProtein-based biomaterialsRegulatory landscape for naturally-derived biomaterialsSolid organ bioengineeringTissue decellularizationTissue engineering

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Naturally-derived biomaterials have a long history of use in regenerative medicine.
  • They are often the preferred choice for functional and useful biomaterial applications.
  • Examples range from simple cell microcarriers to complex decellularized organ scaffolds.

Purpose of the Study:

  • To describe naturally-derived biomaterials used in tissue engineering.
  • To classify these biomaterials based on their composition.
  • To outline current applications of engineered tissues.

Main Methods:

  • Literature review and classification of naturally-derived biomaterials.
  • Analysis of compositional properties.
  • Survey of current applications in regenerative medicine.

Main Results:

  • Classification of naturally-derived biomaterials based on composition.
  • Detailed description of various biomaterials like collagen and alginate.
  • Overview of tissue engineering applications.

Conclusions:

  • Naturally-derived biomaterials are versatile and crucial for tissue engineering.
  • Their classification aids in selecting appropriate materials for specific applications.
  • Engineered tissues derived from these biomaterials have diverse uses in research and medicine.