HIGH MICROANGIOPATHY PREVALENCE IN OBSTRUCTIVE SLEEP APNEA COMORBID TYPE 2 DIABETES PATIENTS

Our aim was to study OSA prevalence in patients with T2DM referred to the ,,Diacor'' and to evaluate the microangiopathy rate among this two groups. Data were obtained from T2DM patients enrolled in a prospective, cohort study. The study was being carried out in the clinic ,,Diacor'' Tbilisi, Georgia. Patients were screened for OSA with the Epworth Sleepiness Scale. Patients scoring more than 11 points were invited to do Nocturnal, laboratory-based polysomnography (PSG) for final diagnoses. The following data were collected: medical anamnesis; demographic and anthropometric data; laboratory (complete blood count, biochemistry, immunology, complete urine test, including microalbuminuria) and instrumental investigation (fundoscophy, laboratory polysomnography) data. From the total 232 patients 54 (23.27%) were diagnosed with OSA. From OSA + patients 12 (22.22%) had coexistence of diabetic retinopathy and microalbuminuria, 19 (35.19%)- coexistence of diabetic retinopathy and chronic kidney disease (CKD). Prevalence of coexisted diabetic retinopathy and CKD and CKD independently was significantly higher in patients with severe than in moderate and mild OSA patients. Our results suggest that it is important to screen all type 2 diabetes patients in Georgia for OSA, as the disease is associated with high prevalence of microangiopathy.