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[Anticoagulant Therapy in Elderly Patients With Atrial Fibrillation]

Y N Belenkov1, G A SHakaryants1, N V Khabarova1

  • 1I.M. Sechenov First Moscow State Medical University (Sechenov University).

Kardiologiia
|October 26, 2018
PubMed

Insights

This paper examines anticoagulant therapy challenges in elderly atrial fibrillation patients, focusing on low-dose risks and adherence issues to improve treatment outcomes.

Area of Science:

  • Geriatric Medicine
  • Cardiology
  • Pharmacology

Background:

  • Atrial fibrillation necessitates anticoagulant therapy for stroke prevention.
  • Elderly patients present unique challenges in managing anticoagulation.
  • Suboptimal dosing and poor adherence are significant clinical concerns.

Purpose of the Study:

  • To review the complexities of selecting anticoagulant therapy for elderly patients with atrial fibrillation.
  • To analyze the risks associated with using low-dose anticoagulants in this population.
  • To explore factors influencing adherence to anticoagulant therapy.

Main Methods:

  • Literature review of studies on anticoagulant use in elderly atrial fibrillation patients.
  • Analysis of data regarding dosing strategies, adverse events, and patient adherence.
  • Discussion of clinical guidelines and best practices.

Main Results:

  • Elderly patients often receive inappropriately low doses of anticoagulants.
  • Low-dose anticoagulation increases the risk of thromboembolic events.
  • Adherence to anticoagulant therapy is frequently suboptimal in this demographic.

Conclusions:

  • Optimizing anticoagulant selection and dosing is crucial for elderly atrial fibrillation patients.
  • Addressing adherence barriers is essential for effective stroke prevention.
  • Further research is needed to refine anticoagulant management strategies for geriatric populations.

Keywords:
adherenceatrial fibrillationdirect oral anticoagulantselderly patientsrivaroxaban

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