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Childhood Obesity and Impact on the Kidney

Liane Correia-Costa1,2,3, Ana Azevedo4,5, Alberto Caldas Afonso4,6,7

  • 1EPIUnit, Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal, lianexcosta@gmail.com.

Nephron
|October 26, 2018
PubMed

Insights

Obesity in children can lead to serious cardiovascular and kidney diseases later in life. Early intervention is crucial to prevent chronic kidney disease and reduce mortality risk in affected children.

Area of Science:

  • Pediatric Nephrology
  • Cardiovascular Health
  • Metabolic Disorders

Background:

  • Obesity is linked to numerous cardiovascular and metabolic issues.
  • Childhood obesity has long-term consequences, increasing cardiovascular event risk.
  • Emerging evidence suggests obesity is an independent risk factor for kidney disease in adults.

Purpose of the Study:

  • To explore the association between childhood obesity and kidney disease risk.
  • To review the role of obesity in the progression of existing kidney impairment.
  • To highlight the need for preventive strategies against obesity-related chronic kidney disease.

Main Methods:

  • Review of longitudinal studies on childhood obesity and comorbidities.
  • Analysis of recent data on obesity and adult kidney disease.
  • Examination of evidence linking overweight/obesity to end-stage renal disease (ESRD) risk.

Main Results:

  • Childhood obesity predicts future cardiovascular events.
  • Obesity exacerbates kidney disease progression and increases mortality risk in children with ESRD.
  • Overweight and obese children face a higher risk of all-cause ESRD later in life.

Conclusions:

  • Childhood obesity is a significant risk factor for developing chronic kidney disease.
  • Understanding the mechanisms is vital for implementing preventive strategies.
  • Addressing childhood obesity is essential for long-term kidney and cardiovascular health.

Keywords:
Body mass indexChronic kidney diseaseKidneyObesityOverweight

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