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Published on: December 6, 2016
The improvement of right ventricular function after adenotonsillectomy in children with obstructive sleep apnea
Dong Yeop Kim1, Kyung Ok Ko1, Jae Woo Lim1
1Department of Pediatrics, Konyang University College of Medicine, Daejeon, Korea.
Insights
Adenotonsillar hypertrophy (ATH) surgery improved right ventricular (RV) function in children with obstructive sleep apnea (OSA). The right ventricular myocardial performance index (RVMPI) showed early improvement, indicating better RV health post-surgery.
Area of Science:
- Pediatric Cardiology
- Sleep Medicine
- Cardiopulmonary Physiology
Background:
- Adenotonsillar hypertrophy (ATH) can cause upper airway obstruction, leading to obstructive sleep apnea (OSA).
- OSA-related chronic hypoxemia may result in pulmonary vasoconstriction and right ventricular (RV) dysfunction.
- Evaluating the impact of surgical intervention on RV function in children with OSA due to ATH is crucial.
Purpose of the Study:
- To assess the effect of adenotonsillectomy (T&A) on right ventricular (RV) function in children with obstructive sleep apnea (OSA) caused by severe adenotonsillar hypertrophy (ATH).
Main Methods:
- Thirty-seven children with OSA due to ATH underwent T&A.
- Transthoracic echocardiography with tissue Doppler imaging (TDE) was used to evaluate mean pulmonary artery pressure (mPAP), tricuspid regurgitation (TR), tricuspid annular plane systolic excursion (TAPSE), and RV myocardial performance index (RVMPI) pre- and post-surgery.
- Follow-up was conducted over 1.78±0.27 years.
Main Results:
- The RVMPI significantly improved post-T&A (P=0.001), suggesting enhanced RV function.
- TAPSE increased in absolute value (P=0.001), but its z-score showed no significant change (P=0.194).
- Mean pulmonary artery pressure (mPAP) and tricuspid regurgitation (TR) parameters did not show significant differences post-T&A.
Conclusions:
- The right ventricular myocardial performance index (RVMPI) measured by TDE may serve as an early indicator of RV function improvement in children with OSA secondary to ATH.
- T&A can positively impact RV function in pediatric OSA patients.
Purpose:
Adenotonsillar hypertrophy (ATH) that causes upper airway obstruction might lead to chronic hypoxemic pulmonary vasoconstriction and right ventricular (RV) dysfunction. We aimed to evaluate whether adenotonsillectomy (T&A) in children suffering from obstructive sleep apnea (OSA) due to severe ATH could improve RV function.
Methods:
Thirty-seven children (boy:girl=21:16; mean age, 9.52±2.20 years), who underwent T&A forsleep apnea due to ATH, were included. We analyzedthe mean pulmonary artery pressure (mPAP), the presence and the maximal velocity of tricuspid regurgitation (TR), the tricuspid annular plane systolic excursion (TAPSE), and the right ventricular myocardial performance index (RVMPI) with tissue Doppler echocardiography (TDE) by transthoracic echocardiography pre- and post-T&A. The follow-up period was 1.78±0.27 years.
Results:
Only the RVMPI using TDE improved after T&A (42.18±2.03 vs. 40±1.86, P=0.001). The absolute value of TAPSE increased (21.45±0.90 mm vs. 22.30±1.10 mm, P=0.001) but there was no change in the z score of TAPSE pre- and post-T&A (1.19±0.34 vs. 1.24±0.30, P=0.194). The mPAP was within normal range in children with ATH, and there was no significant difference between pre- and post-T&A (19.6±3.40 vs. 18.7±2.68, P=0.052). There was no difference in the presence and the maximal velocity of TR (P=0.058).
Conclusion:
RVMPI using TDE could be an early parameter of RV function in children with OSA due to ATH.
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