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Iron status in small for gestational age and appropriate for gestational age infants at birth

Hyeon A Kim1, Sook-Hyun Park1, Eun Joo Lee1

  • 1Department of Pediatrics, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.

Korean Journal of Pediatrics
|October 26, 2018
PubMed

Insights

Small for gestational age (SGA) infants have lower iron stores at birth compared to appropriate for gestational age (AGA) infants. Monitoring iron deficiency is crucial for SGA infants, especially those born to mothers with hypertension.

Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Iron Metabolism

Background:

  • Infant iron status is critical for development.
  • Small for gestational age (SGA) infants may face nutritional challenges.
  • Gestational age and birth weight influence neonatal health outcomes.

Purpose of the Study:

  • To compare the iron status of small for gestational age (SGA) and appropriate for gestational age (AGA) newborns.
  • To identify potential risks for iron deficiency in SGA infants.

Main Methods:

  • Retrospective review of clinical data for 904 neonates.
  • Analysis of serum ferritin levels as a marker of iron status within 24 hours of birth.
  • Comparison of iron markers between SGA and AGA infant groups.

Main Results:

  • SGA infants exhibited higher hematocrit levels but similar initial serum ferritin compared to AGA infants.
  • Adjusted analysis revealed significantly lower serum ferritin levels in SGA infants.
  • Total body iron stores were found to be lower in SGA infants.

Conclusions:

  • SGA infants demonstrate reduced iron stores at birth.
  • Maternal hypertension in late preterm SGA infants increases the risk of inadequate iron stores.
  • Routine monitoring for iron deficiency is recommended for SGA infants during follow-up.
Abstract

Keywords:
Iron storesNeonateSmall for gestational age

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