Multifunctional and Programmable Modulated Interface Reactions on Proteinosomes
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Updated: Feb 3, 2026

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
Published on: March 9, 2017
Pei Zhou1, Shuang Wu2, Xiaoman Liu1
1MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, The Key Laboratory of Microsystems and Microstructures Manufacturing, Ministry of Education, School of Chemistry and Chemical Engineering , Harbin Institute of Technology , Harbin 150001 , China.
Abstract:
A multiresponsive microcapsule has been synthesized by incorporating photoswitchable spiropyran units and the thermoresponsive monomer N-isopropylacrylamide into membrane lumens. By using functionalized light or thermoresponsive groups, this multifunctional microcapsule can modulate programmed release and interface reactions between lipase and fluorescein diacetate, alkaline phosphatase and fluorescein diphosphate, and others. Exposing this multifunctional microcapsule in a programmed controlled way allowed us to develop schematics to understand complicated interface interactions on protocells.
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