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Ginger and Testosterone.

Saleem Ali Banihani1

  • 1Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan. sabanihani@just.edu.jo.

Biomolecules
|October 27, 2018
PubMed
Summary

Ginger supplementation may enhance testosterone production in males, particularly under oxidative stress. Research suggests mechanisms like increased luteinizing hormone and testicular support, but human studies are needed for confirmation.

Area of Science:

  • Endocrinology
  • Male Reproductive Health
  • Natural Product Research

Background:

  • Testosterone is a crucial male sex hormone, and its production is a significant research target.
  • Dietary supplements and medicinal plants are explored for their potential to enhance male testosterone levels.
  • Ginger (Zingiber officinale) has been investigated for its link to testosterone since 1991.

Purpose of the Study:

  • To systematically review and summarize the effects of ginger and its extracts on testosterone production in males.
  • To consolidate existing research findings on the ginger-testosterone relationship.

Main Methods:

  • Comprehensive literature search of PubMed, Scopus, and Web of Science databases (November 1991 - August 2018).
  • Inclusion of English language articles (full text or abstracts) using keywords 'ginger' and 'Zingiber officinale' versus 'testosterone'.
Keywords:
Zingiber officinalegingergingeroltestosterone

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  • Review of references from relevant published articles.

    • Main Results:

    • Ginger supplementation, especially under oxidative stress, appears to enhance testosterone production in males.
    • Identified mechanisms include increased luteinizing hormone, testicular cholesterol, antioxidant enzyme activity, and testicular blood flow.
    • Other proposed mechanisms involve reduced oxidative stress, normalized blood glucose, increased testicular weight, and testosterone receptor recycling.

    Conclusions:

    • The majority of research indicates a positive association between ginger and enhanced testosterone production in males.
    • Current evidence is primarily derived from in vivo and basic research; human clinical data is lacking.
    • Further clinical studies are imperative to confirm the effects of ginger on human testosterone levels.