Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nursing Implementation01:15

Nursing Implementation

6.2K
Implementation is the execution of the nursing care plan developed during the planning phase.
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
6.2K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

3.9K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
3.9K
Guidelines for Nursing Documentation I01:30

Guidelines for Nursing Documentation I

1.9K
Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:  
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
1.9K
Guidelines for Sketching a Curve01:23

Guidelines for Sketching a Curve

134
Curve sketching is a systematic method for understanding the overall behavior of a function by analyzing its key mathematical features. A function defines a curve on the coordinate plane, where the horizontal axis represents the input variable and the vertical axis represents the output. The process begins by determining the domain, which specifies the set of input values for which the function is defined and establishes the horizontal extent of the graph.Intercepts with the horizontal and...
134
Guidelines for Nursing Documentation II01:26

Guidelines for Nursing Documentation II

1.7K
Effective documentation is an integral part of nursing practice. Here are some essential guidelines to follow when documenting patient care:
Timely documentation is crucial to ensure continuity of care for patients. Any delays in recording or reporting medical information can result in medical errors and even adverse patient outcomes. From medication administration to diagnostic test results, every detail must be accurately and promptly documented to provide the best possible care for patients.
1.7K
Legal Guidelines for Documentation01:06

Legal Guidelines for Documentation

2.1K
The legal guidelines for nursing documentation are essential for ensuring accurate, professional, and ethical recording of patient care. The guidelines are discussed here:
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between state-level kratom regulations and poison center-reported severe medical outcomes and healthcare use: A United States national analysis.

Addiction (Abingdon, England)·2026
Same author

The BIOPREVENT machine-learning algorithm predicts chronic graft-versus-host disease and mortality risk using posttransplant biomarkers.

The Journal of clinical investigation·2026
Same author

The Association Between Preoperative Tamsulosin Use and Intraoperative Hypotension.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Evaluating the Role of Erythrocyte-Related Markers in Predicting Adenosine Response in Supraventricular Tachycardia.

The Annals of pharmacotherapy·2026
Same author

Treatment with asciminib after a prior tyrosine kinase inhibitor in patients with chronic-phase chronic myeloid leukemia.

Leukemia research·2025
Same author

Longer time from diagnosis to initiation of hypomethylating agents plus venetoclax for acute myeloid leukemia does not worsen survival: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND).

Haematologica·2025

Related Experiment Video

Updated: Feb 3, 2026

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

16.9K

Implementation and evaluation of high-dose methotrexate administration guidelines.

Thomas J Nowak1, Aaron H Lorge1, Lisa E Rein1

  • 1Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA.

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
|October 27, 2018
PubMed
Summary

Implementing new high-dose methotrexate guidelines, which increased the supportive care discontinuation threshold to 0.1 µmol, reduced supportive care duration. This change in methotrexate protocols may allow for earlier hospital discharge.

Keywords:
Adherencedischargeguidelinemethotrexatesupportive care

More Related Videos

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

7.0K
Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
05:44

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery

Published on: November 14, 2018

21.2K

Related Experiment Videos

Last Updated: Feb 3, 2026

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

16.9K
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

7.0K
Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
05:44

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery

Published on: November 14, 2018

21.2K

Area of Science:

  • Oncology
  • Pharmacology
  • Clinical Pharmacy

Background:

  • High-dose methotrexate (HDMTX) is a critical chemotherapy for various cancers.
  • Current protocols for supportive care and methotrexate level thresholds for discontinuation lack consistency.
  • This study evaluated new HDMTX administration guidelines with an elevated threshold for supportive care cessation.

Purpose of the Study:

  • To assess the impact of revised high-dose methotrexate administration guidelines on supportive care duration.
  • To determine if a higher methotrexate level threshold for supportive care discontinuation affects patient outcomes.
  • To evaluate the efficiency of supportive care management in high-dose methotrexate therapy.

Main Methods:

  • A single-center, observational study analyzed patients receiving HDMTX.
  • Data collected retrospectively and prospectively from January 2015 to May 2017.
  • Primary endpoint: time to discontinuation of sodium bicarbonate infusion post-methotrexate administration.

Main Results:

  • The median time to sodium bicarbonate discontinuation was shorter in the prospective group (73.2 hours) compared to the retrospective group (97.7 hours).
  • Secondary outcomes, including hospitalization duration and laboratory monitoring frequency, also favored the prospective group.
  • Adherence to the revised guideline was assessed in the prospective analysis.

Conclusions:

  • Implementation of HDMTX guidelines with a 0.1 µmol threshold for supportive care discontinuation decreased supportive care duration.
  • The revised guidelines show potential for optimizing patient management and facilitating earlier hospital discharge.
  • Further research may be needed to confirm statistical significance in early discharge rates.