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Related Concept Videos

Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Mitral Valve Prolapse II: Assessment and Management01:22

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IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

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The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
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Review and Preview01:10

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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
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Review and Preview01:13

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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Kidney Structure01:45

Kidney Structure

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The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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Interrelationship Between Kidney Function and Percutaneous Mitral Valve Interventions: A Comprehensive Review.

Kevin Bryan Lo1, Sandeep Dayanand2, Pradhum Ram1

  • 1Department of Medicine, Einstein Medical Center, Philadelphia, PA, United States.

Current Cardiology Reviews
|October 27, 2018
PubMed
Summary

Percutaneous mitral valve repair may improve renal function, especially in those with existing kidney issues. However, patients with Chronic Kidney Disease (CKD) still face higher long-term risks and mortality after the procedure.

Keywords:
Percutaneous mitral repairchronic kidney diseasemitraclippatient outcomesrenal functionreview.

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Area of Science:

  • Cardiology
  • Nephrology
  • Interventional Cardiology

Background:

  • Percutaneous mitral valve repair offers an alternative for mitral regurgitation, particularly in high-surgical-risk patients.
  • The impact of renal dysfunction on percutaneous mitral valve repair outcomes and vice versa is an evolving area of research.

Purpose of the Study:

  • To evaluate the effects of percutaneous mitral valve repair on renal function.
  • To assess the long-term outcomes of patients with Chronic Kidney Disease (CKD) undergoing percutaneous mitral valve repair.

Main Methods:

  • Review of current evidence on percutaneous mitral valve repair and renal function.
  • Analysis of patient outcomes, including mortality and hospitalization, stratified by baseline renal function and CKD status.

Main Results:

  • Percutaneous mitral valve repair is associated with improved cardiac function, hemodynamics, and renal function, with greater improvement in patients with baseline renal dysfunction.
  • Patients with Chronic Kidney Disease (CKD) experience poorer long-term outcomes, including increased mortality and hospitalization, irrespective of post-repair GFR improvements.
  • The adverse impact of CKD on outcomes is more pronounced in patients with GFR < 30 mL/min/1.73 m².

Conclusions:

  • Proper patient selection is crucial for percutaneous mitral valve repair, balancing potential renal benefits against CKD-related risks.
  • Standardized criteria are needed for patient selection for percutaneous mitral valve repair, particularly for devices like Mitraclip.
  • Further research is required to optimize long-term outcomes in patients undergoing percutaneous mitral valve repair, especially those with renal comorbidities.