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Nickel-catalyzed intermolecular carboiodination of alkynes with aryl iodides
Toshifumi Takahashi1, Daiki Kuroda, Toru Kuwano
1Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. kurahashi.takuya.2c@kyoto-u.ac.jp matsubara.seijiro.2e@kyoto-u.ac.jp.
Abstract:
Nickel-catalyzed intermolecular carboiodination of alkynes with aryl iodides to form highly substituted and functionalized alkenyl iodides has been developed. The reaction involves radical-mediated formal alkyne insertion into the carbon-nickel bond and carbon-iodine reductive elimination facilitated by Ni(iii) species.
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