Related Experiment Video
Updated: Feb 3, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
MRI evaluation of diffuse subcutaneous neurofibroma of the lower limb in a low resource setting
Adenike Temitayo Adeniji-Sofoluwe1, Olanrewaju Adebusuyi Ogunleye2, Clement Abu Okolo3
1Department of Radiology, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.
Abstract:
An unusual type of neurofibroma predominantly seen in children and young adults is diffuse neurofibroma. We present a 25-year-old female with recurring soft tissue masses in her right lower limb. MRI showed areas of T 1 iso-intensity and T 2 hyperintensity relative to skeletal muscle within the subcutaneous fat. These masses show marked enhancement post gadolinium administration. Histological examination of the excised mass showed diffuse neurofibroma. The rare nature of this tumour and the limited literature describing the imaging features make the diagnosis relatively difficult for a radiologist.
More Related Videos
Related Concept Videos
Short-distance Transport of Resources
Diffusion
Diffusion
Arteries of Lower Limbs
Veins of Lower Limbs
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
Facilitated Diffusion
In this process, substrates such as organic compounds and ions interact with a transporter on one side, triggering conformational changes in proteins that enable...

