Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Centrosome Duplication

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...

Gene Duplication and Divergence

Gene Duplication and Divergence

The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...

Duplication of Chromatin Structure

Duplication of Chromatin Structure

The process of chromosome duplication during cell division requires genome-wide disruption and re-assembly of chromatin. The chromatin structure must be accurately inherited, reassembled, and maintained in the daughter cells to ensure lineage propagation.
The basic unit of the chromatin is the nucleosome, consisting of DNA wrapped around octameric histone proteins and short stretches of linker DNA separating individual nucleosomes. The histone proteins within the nucleosome have their...

Diagnosing Acidosis and Alkalosis

Diagnosing Acidosis and Alkalosis

Diagnosing acid-base imbalances involves systematically analyzing arterial blood samples, focusing on three key measurements: pH, bicarbonate (HCO3−) concentration, and carbon dioxide partial pressure (PCO2). This analysis follows a four-step process that helps identify the imbalance's underlying cause and nature.
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2 and...

Radiological Investigation I: X-ray and CT

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...

Trial and Error and Algorithm

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pockets of Trouble: Diffuse Jejunal Diverticulosis Causing Refractory Intestinal Microbial Overgrowth.

ACG case reports journal·2026

Same author

Refractory Dysphagia: A Case of Coexisting Eosinophilic Esophagitis and Achalasia.

The American journal of gastroenterology·2025

Same author

Radiographic Identification of Visceroptosis in Patients With Hypermobile Ehlers-Danlos Syndrome With Functional Gastrointestinal Symptoms Compared With Healthy Subjects.

Clinical and translational gastroenterology·2025

Same author

Trends in rhinoplasty: Insights from an international survey of facial plastic surgeons.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2025

Same author

Plummer-Vinson Syndrome: Classic Triad of Iron Deficiency Anemia, Dysphagia, and Esophageal Webs.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2024

Same author

Percutaneous CT-Guided Cryoablation of the Salivary Glands in a Porcine Model.

Journal of vascular and interventional radiology : JVIR·2016

Search research articles

Related Experiment Video

Updated: Feb 3, 2026

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Published on: August 16, 2020

Diagnosing urethral duplication including a novel radiological diagnostic algorithm.

Jonathan Frankel¹, Richard Sukov¹

¹Department of Radiology, Cedars Sinai Medical Center, Los Angeles, CA, USA.

BJR Case Reports

|October 27, 2018

Summary

This case study highlights urethral duplication, a rare genitourinary anomaly. A diagnostic algorithm is proposed to improve imaging for this condition, minimizing radiation and cost.

More Related Videos

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Published on: July 23, 2020

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

Related Experiment Videos

Last Updated: Feb 3, 2026

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Published on: August 16, 2020

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Published on: July 23, 2020

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

Area of Science:

Urology
Medical Imaging
Anatomy

Background:

Urethral duplication is a rare congenital genitourinary anomaly.
It typically presents in pediatric and adolescent populations.
Adult presentation is uncommon, often linked to sexual activity.

Observation:

A 24-year-old male presented with penile glans irritation during intercourse.
Imaging revealed urethral duplication.
Subtype classification was crucial for surgical planning.

Findings:

Urethral duplication management requires accurate subtype identification.
Literature review reveals varied diagnostic approaches.
Existing methods may involve unnecessary radiation, invasiveness, and cost.

Implications:

A strategic diagnostic algorithm is presented for suspected urethral duplication.
The algorithm aims to provide essential clinical information efficiently.
It focuses on minimizing radiation exposure, invasiveness, and healthcare costs.