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Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson's Disease
Alessandra Fanciulli1,2, Georg Goebel3, Bernhard Metzler4
1Department of Neurology Innsbruck Medical University Innsbruck Austria.
Background And Methods:
To investigate the possible efficacy of an elastic abdominal binder to control orthostatic hypotension (OH) associated with Parkinson's disease (PD), 15 patients with PD and OH were enrolled in a single-blind crossover study with elastic abdominal versus placebo binder on two different days, separated by a 1-day interval, followed by a 4-week open-label follow-up.
Results:
Intervention significantly reduced blood pressure fall upon tilting. The mean difference (standard deviation; 95% confidence intervals) between abdominal binder versus placebo was +10 mm Hg (10.2; +3.5, +16.5; P = 0.006). No significant effect on supine mean blood pressure values was observed compared to placebo (P = 0.3). Symptoms of OH decreased significantly during follow-up (P = 0.003), as assessed by means of the Orthostatic Hypotension Questionnaire.
Conclusions:
Our findings suggest that elastic abdominal binders may be a simple complementary tool to alleviate OH in PD.