Nocturia in Patients With Parkinson's Disease

Area of Science:

• Neurology
• Urology

Background:

• Nocturia, or waking to urinate, is a common non-motor symptom in Parkinson's disease (PD).
• The underlying causes of nocturia in PD remain poorly understood.
• This study aimed to investigate lower urinary tract (LUT) symptoms in PD patients with nocturia.

Purpose of the Study:

• To evaluate lower urinary tract (LUT) symptoms in Parkinson's disease (PD) patients reporting nocturia.
• To assess the impact of nocturia on the quality of life and sleep in PD patients.
• To determine the prevalence of nocturnal polyuria in PD patients with nocturia.

Main Methods:

• Included 23 Parkinson's disease patients with nocturia.
• Utilized 3-day bladder diaries to record fluid intake, urinary output, and voiding times.
• Administered standardized questionnaires for LUT symptoms (Urinary Symptom Profile, International Prostate Symptom Score, Qualiveen Short Form) and sleep quality (Parkinson's Disease Sleep Scale).

Main Results:

• 56.5% of patients exhibited nocturnal polyuria (Nocturnal Polyuria Index > 0.33).
• Patients with nocturnal polyuria reported more severe LUT symptoms.
• Nocturnal polyuria was associated with a greater impact on quality of life and sleep, though not statistically significant.

Conclusions:

• Nocturnal polyuria is prevalent in Parkinson's disease patients experiencing nocturia.
• Nocturnal polyuria appears to negatively affect quality of life and sleep in this population.
• Bladder diaries are crucial for assessing nocturia in Parkinson's disease patients.